EURotiales Functional GENomics Consortium
The Eurotiales is a wide group of fungi best known for the Aspergillus and Penicillium species that are used in medicine and industry. The large number of Eurotiales species and their societal importance makes this an ideal group of fungi for detailed comparative and functional (post-)genomics.
Aspergillus and Penicillium are not only among the most important fungi for use in biotechnology, they are also among the most commonly found groups of fungi in environments worldwide. Due to its relevance for industry, for medicine, and their use as model systems for fungal biology, Aspergillus has one of the largest research communities in the fungal field. Indeed, this has resulted in this genus currently being the most intensively studied fungi with respect to genomics, with genome sequences for nine species publicly available and two more in progress.
The availability of the new genomes in combination with the tools developed for Aspergillus genomics (e.g. AspGD and CADRE) enables comparative genomics at a much more detailed level than is possible for other fungi. Comparative studies have been performed on several aspects of the biology of the genus, but we feel that adding genomes of additional species to this group will significantly enhance our understanding of the biology of both the Aspergilli and fungi in general.
As a result of our proposal granted in CSP2011, JGI will sequence eight Aspergillus species (A. tubingensis, A. brasiliensis, A. acidus, A. glaucus, A. versicolor, A. sydowii, A. wentii, A. zonatus) and one Penicillium species (P. chrysogenum), to complement those genome sequences already available for the aspergilli and strengthen the genomic data available for comparative studies with the closely related and economically important genus Penicillium. This analysis will be strengthened by other genome projects addressing Eurotiales species, such as the Penicillium genome project currently running in France.
Ronald P. de Vries
Jennifer Russo Wortman
Patricia (Trish) A. vanKuyk
Visiting address: CBS-KNAW Fungal Biodiversity Centre
Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
Postal address: CBS-KNAW Fungal Biodiversity Centre
P.O. Box 85167
3508 AD, Utrecht
Phone: +31 (0)30 21 22 600
Fax: +31 (0)30 21 22 601
Prof. Dr. Ronald P. de Vries
Fungal Growth Database
Fungal Stress Database
Eurotiales Functional Genomics